2-Methyl-2-(2-thienyl)propanoic acid - Names and Identifiers
2-Methyl-2-(2-thienyl)propanoic acid - Physico-chemical Properties
Molecular Formula | C8H10O2S
|
Molar Mass | 170.23 |
Storage Condition | Room Temprature |
Sensitive | Irritant |
MDL | MFCD13563034 |
2-Methyl-2-(2-thienyl)propanoic acid - Introduction
2-Methyl-2-(2-thienyl)propanoic acid(2-methyl -2-(2-thienyl) propionic acid) is an organic compound with a chemical formula of C10H12O2S and a molecular weight of 192.27.
The following is about the properties of 2-Methyl-2-(2-thienyl)propanoic acid:
-Appearance: White crystalline solid
-melting point: 82-84 ℃
-Boiling point: 234-240 ℃
-Solubility: Slightly soluble in water, soluble in organic solvents such as alcohol and ether.
2-Methyl-2-(2-thienyl)propanoic acid is mainly used in the synthesis of pharmaceutical intermediates, especially as a precursor of non-steroidal anti-inflammatory drugs (NSAIDs). It has anti-inflammatory, analgesic and antipyretic activities. Common drugs such as phenalapril, lidocaine, and hydroxybenzobutyric acid may also contain this structure.
2-Methyl-2-(2-thienyl)propanoic acid can be prepared by the following methods:
1. reacting 2-thiophene methanol with acetone to generate a methylated product;
2. Then, the methylene product is acidified, and then the target product is prepared through appropriate process steps.
About safety information:
- 2-Methyl-2-(2-thienyl)propanoic acid is irritating to the eyes, skin, and respiratory tract. Wear appropriate protective equipment when using or processing the compound.
-Avoid inhaling dust or vapor from the solution and ensure good ventilation.
-If the substance is exposed externally, rinse the affected area immediately with plenty of water and seek medical advice if necessary.
In general, 2-Methyl-2-(2-thienyl)propanoic acid is an important drug intermediate with wide application potential. Be sure to pay attention to safety during use.
Last Update:2024-04-09 20:00:08